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Proceedings of The First International Conference on Systems Biology The 9th JST International Symposium
Vol. 1 (2000) p.251
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Integrative Modeling of Mitochondrial Energy Metabolism
Katsuyuki Yugi1)2) and Masaru Tomita1)3)
1) Laboratory for Bioinformatics
2) Graduate School of Media and Governance
3) Department of Environmental Information, Keio University
  We are in the process of constructing a kinetic model of mitochondrial energy metabolism including the electron transport (respiratory chain), the TCA cycle, the fatty acid metabolism (β oxidation), and the inner-membrane metabolite carriers. In this work, we report a model of these metabolic pathways that has been recently completed using the E-CELL system [2], a generic simulation environment we have developed for cellular simulation.

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