 | A cell-sorting model can explain cone mosaic pattern of medaka
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| | Shusaku Tohya1), Atsushi Mochizuki1) and Yoh Iwasa1) |
| | 1) Department of Biology, Faculty of Sciences, Kyushu University |
| | In fish retina, four types of cone photoreceptor cells with different sensitive wavelength of the light (blue, UV, red and green) are arranged in regular pattern, called “cone mosaic”. A pair of small cones, one sensitive to red and the other sensitive to green is close in contact and forms a “double cone”. The development of cone mosaic has been studied by various experiental techniques, however a mechanism of formation of cone mosaic has not been identified yet. We study the mechanism of formation by analyzing models in which calls are arranged on the 2-dimensional surface, experience interaction between neighbors, and automatically form the regular pattern. We demonstrated that medaka mosaic pattern can neighbors at a rate affected by cell-cell adhesions. |
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