 | ウィスコンシンカード分類課題遂行中のサル前頭前野から記録された分類規則の作業記憶および行動の誤りを表す神経活動
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| | Farshad A. Mansouri1), 松元 健二2), 田中 啓治1)2) |
| 1) CREST·JST
2) 理研脳センター認知機能表現研究チーム |
| | Two monkeys were trained to perform a computerized version of WCST with two dimensions. The relevant attribute had to be found by trial and error. Single cell recording was conducted from lateral prefrontal cortex of one monkey. From 153 task-correlated cells, 59% showed differential activity at some periods of the task depending on the relevant rule and 63% showed reward-related activity. 60% of cells responded to error signal and 37% of them fired differentially in perseverative and fixation-error trials. These results suggest that prefrontal cells participate in accomplishing WCST by representing behavioral outcome and the working memory of the rule. |
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